Winter Skin Concerns, Can Skin Boosters Help?

Hello, I am Dr. Sang-ju Lee, a board-certified dermatologist. Cold and dry winter is a particularly vulnerable season for our skin. Indoor heating devices, such as heaters, can make the skin even drier. In such cases, many people consider skin booster treatments like Juvelook, Rejuran, and Water-Luminous Injection for moist and healthy skin. Today, I will compare which of the three representative skin boosters – Water-Luminous Injection, Rejuran, and Juvelook – might be suitable for you.

Skin boosters are treatments that inject active ingredients into the skin to improve skin health. They can be broadly divided into three generations:

• 1st Generation Skin Booster: Water-Luminous Injection
  • Mainly composed of hyaluronic acid, it provides moisture to the skin.
• 2nd Generation Skin Booster: Rejuran
  • With PN (polynucleotide) extracted from salmon DNA, it helps restore and regenerate damaged skin.
• 3rd Generation Skin Booster: Juvelook
  • The latest skin booster that promotes collagen production, which is key to skin regeneration and elasticity.

In addition to these, there are various other skin boosters, but Water-Luminous Injection, Rejuran, and Juvelook are highly regarded for their effectiveness and safety, and are loved by many. As a dermatologist, having experienced various skin booster treatments, I personally feel that Juvelook is effective in many aspects. Therefore, today I will compare the effects and pros/cons of Water-Luminous Injection and Rejuran, focusing on Juvelook.

Water-Luminous Injection is a relatively simple skin booster treatment that can be received without much burden. The hyaluronic acid component, naturally present in the skin, attracts surrounding moisture, making the skin moist and vibrant, and helps improve fine wrinkles.

However, since hyaluronic acid gradually breaks down and disappears in the body after treatment, its effect is usually temporary, lasting about 2-4 weeks, or up to 6 weeks. Also, there are limitations in improving deep wrinkles.

Juvelook works by stimulating skin fibroblasts with PDLLA to promote collagen production. Therefore, rather than immediate effects, it is characterized by a relatively longer-lasting effect of 3 to 6 months, or even up to 1 year, and the expectation of natural skin improvement.

In particular, Juvelook combines PDLLA and hyaluronic acid to help improve both skin elasticity and texture simultaneously. Some medical institutions also report that adding Water-Luminous Injection components to this mixture during treatment can have a positive effect not only on moisturizing but also on improving elasticity.

Rejuran contains PN (polynucleotide) extracted from salmon DNA, which helps improve damaged skin tissue, making the skin healthy and elastic.

Rejuran is known to be effective for damaged or inflamed skin, but the treatment can be painful. Also, like most skin boosters, it is often considered a drawback that it achieves indirect effects by injecting beneficial nutrients into the skin.

Each skin booster has its unique advantages and characteristics.

• Juvelook: The PDLLA component induces the skin to form its own collagen, leading to a direct increase in collagen and elastin, allowing for clear treatment effects.
• Rejuran: The PN component improves damaged skin tissue, but it works by injecting nutrients for indirect effects, and pain may be involved.
• Water-Luminous Injection: Provides moisture to the skin with hyaluronic acid, but the duration of its effect is relatively short.

The most suitable skin booster varies depending on each individual's skin condition, desired effects, and budget. The three boosters introduced today – Juvelook, Water-Luminous Injection, and Rejuran – have slightly different characteristics, effects, and indications, so careful selection is important.

So far, I have compared the representative skin booster treatments: Water-Luminous Injection, Juvelook, and Rejuran. If you have any questions, please contact a medical institution.